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Airway Pressure Release Ventilation (APRV, Bivent)

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Tips:

Use Peak Airway Pressure in Pressure Modes and Plateau Pressures in Volume Modes of Ventilation to determine initial P1 setting.

 A recruitment maneuver of 40 cmH2O of peep for 40 seconds can be done after circuit changes, replacement of expiratory filters, changing of Ballard suction catheters, going to/returning from transport where patient was manually bagged, or by physician written order.

Initiate weaning for conventional management if:

Physiologic parameters are acceptable

Spo2 >92%, fio2 60%

EtCO2 <58 mmHg

ABG = pH >7.30, PaCO2 <50 mmHg, Pao2 >60 mmHg

Resolving disease / trauma process

“Drop and Stretch” method of weaning:  reduce level of P high and increase T high until mode is converted to CPAP as a method of SBT before extubation. Dropping and stretching too quickly leads to derecruitment of alveoli.

Notes:

-T1 and T2 will need to be adjusted clinically. 

-Release Rate(cycles/minute)=60/(T1+T2).  This rate should not be>12

-Results are not instantaneous.  The PaO2 will continue to improve as more alveoli are recruited. (PaO2 of 60mmHg is low end)

-For obstructive lung disease patients, use longer T2 times

-T2 should be titrated to allow between 50% and 75% of the volume out of the lung (look at the flow waveform)

-Patients will have retained lung volume, (This is not true auto-PEEP and is a desired effect of APRV)

-LONGER T1 AND SHORTER T2 = MORE RECRUITMENT/OXYGENATION AND LESS CO2 CLEARANCE

-SHORTER T1 AND LONGER T2 = LESS RECRUITMENT AND MORE CO2 CLEARANCE

-MOST SPONTANEOUSLY BREATHING PTS WILL REGULATE THEIR OWN CO2.   Always allow as much spontaneous breathing as possible. 

-Do not use neuromuscular blockade. 

-Worry about oxygenation first and the CO2 second. (ph of 7.20, think permissive hypercapnia.)

-If patient is inhaling too forcefully and using accessory muscles: may still be under-recruited. Can increase P1, or decrease T2 as long as <75% PEFR maintained on flow curve.

-If patient is exhaling too forcefully: may be overinflated (also diaphragm will be flat on CXR). Can decrease P1 and increase T1 to maintain the same mean airway pressure, or increase the T2 as long as >25% of PEFR maintained on flow curve.